Hengshui Bohai Chemical Technology Co., Ltd

Call us toll free:
+8618631898150
Home Products Intermediate Product Glycine

Products

Glycine
Glycine Glycine Glycine Glycine

Glycine

Product ID : A-100
Product Attributes :
Synonym(s):
Glycine, Gly, Aminoacetic acid, Aminoethanoic acid, Glycocoll
Linear Formula:
NH2CH2COOH


Product Description

General description

A non-essential, optically inactive, non-chiral amino acid. It is the smallest of the 20 natural amino acids. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.
A nonpolar, uncharged amino acid.

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Appearance :

Crystalline

Physical State :

Solid

Solubility :

Soluble in water (100 mg/ml), and acetone (slightly soluble). Insoluble in alcohol, and ether.

Storage :

Store at room temperature

Melting Point :

240° C

Boiling Point :

~240.90° C at 760 mmHg (Predicted)

Density :

1.60 g/cm3 at 20° C

Refractive Index :

n20D 1.46 (Predicted)

IC50 :

Glycine receptor alpha-4 chain: IC50 = 6 µM (mouse); Glutamate NMDA receptor: IC50 = 0.2 µM (rat)

Ki Data :

Glutamate NMDA receptor: Ki= 170 nM (rat)

pK Values :

pKa: 2.43 (Predicted), pKb: 9.64 (Predicted)


Online Inquiry